Carb loaded meals and obesity are detrimental to the heart. A new mechanism explored.

“It is thought to be common sense that carbohydrate loading is detrimental; but the negative effects are delivered through the principal hormones, the natriuretic peptides, produced by your heart, a system that is suppressed in obese individuals,”

“Before the participants began the study, they were normalized on a standard diet for a couple of days to remove any background dietary variability. The investigators observed that drinking the high-carb shake led to a 25 percent reduction in ANP in participants over the course of several hours.”